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A systematic review assessing the effects of ashwagandha for anxiety and stress response included five randomized controlled human trials. An analysis of results indicated that ashwagandha intervention resulted in greater score improvements than placebo in outcomes shown on anxiety or stress scales, with no observed adverse events.
SHODEN® INDUSTRY-LEADING CONCENTRATION SUPPORTS A MORE RESTFUL NIGHT SLEEP
Shoden® Ashwagandha Extract Shoden is an extract derived from the leaves and roots of the ashwagandha plant. This multi-patented ashwagandha extract is distinguished by its industry-leading concentration of 35% withanolide glycosides. Shoden has been clinically studied for its adaptogenic role in the stress response and for support of a more restful night sleep. Additionally, studies designed specifically to assess the safety of Shoden resulted in no adverse or toxic effects. Company Name’s Ashwagandha Complete contains 240 mg of Shoden per the two-capsule daily dose.
A randomized, double-blind, placebo-controlled trial in adults (N = 60) was designed to assess the stress-balancing effects and the potential mechanism of action of Shoden. Test subjects given 240 mg of Shoden daily for 60 days demonstrated reduced levels of the stress hormone cortisol and the steroidal hormone DHEA-S. There was also an increase of testosterone in male participants. Although other potential mechanisms of action were not investigated, the results of this study suggested ashwagandha has an attenuating effect on the hypothalamic-pituitary-adrenal axis activity in stressed individuals.
Results from a randomized, controlled trial in adult males (N = 57) with moderate fatigue who were given Shoden daily for 16 weeks indicated significant improvements in salivary levels of the steroid hormones DHEA-S and testosterone, which typically decline with age. Additionally, although insignificant, self-reported improvements in fatigue, vigor, and sexual and psychological well-being were documented via questionnaire. No significant difference was recorded for salivary cortisol levels; however, it should be noted that in previous findings serum rather than salivary cortisol was assessed.
To ascertain the effect of Shoden on restorative sleep, healthy subjects (N = 150) were given 120 mg of Shoden daily for 6 weeks in a double-blind, placebo-controlled study. The overall quality of sleep was evaluated using a weekly questionnaire and an assessment of parameters such as sleep latency, sleep efficiency, and total sleep time as measured by a wearable sleep actigraphy diagnostic monitoring device. A significant improvement of sleep measures that define non-restorative sleep were noted in the treatment group when compared to placebo, demonstrating the positive effect of Shoden on encouraging restful sleep.
Take one to two capsules daily, or as directed by your healthcare professional.
FORMULATED TO EXCLUDE
Wheat, gluten, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified
organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Distributed By InnerLight Remedies
1410 Northern Blvd #1013
Manhasset, NY 11030
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Food must be broken down into its component parts in order to be absorbed into the bloodstream. Though salivary secretions, chewing, gastric acid, and pepsin begin the process of digestion, the majority of digestion takes place farther down the gastrointestinal tract in the small intestine. Once food leaves the stomach and enters the small intestine, digestive enzymes begin the monumental task of turning it into the building blocks and fuel that the body needs for structural support and metabolic processes. Digestive enzymes are produced primarily in the pancreas and brush border of the small intestine, and the health and function of these organs is vital to effective digestion and absorption. Proteolytic enzymes, amylases, and lipases are responsible for the digestion of proteins, carbohydrates, and fats. The complete digestion of these macronutrients produces small peptides, amino acids, monosaccharides and disaccharides, and free fatty acids that can easily pass through the intestinal microvilli and enter the bloodstream. Healthy digestion assures that incompletely digested molecules and proteins don’t enter the bloodstream where they may be recognized as “foreign” by a vigilant immune system.
Pancreatic and Intestinal Enzymes
Pancreatic production of proteases, amylases, and lipases is complemented byintestinal production of lactase, maltase, sucrase, enterokinase, and various peptidases, highlighting the importance of the pancreas and the intestines in the digestive process. The enzyme lactase is required to break down lactose into glucose and galactose before the intact lactose can draw excess water into the bowel, and before colonic bacteria can break it down into volatile gases and acids. Though lactose (a disaccharide found only in mammals’ milk) is readily digested by most infants, normal production decreases as a child is weaned onto whole foods and may eventually cease in adulthood. Exogenous administration of lactase can support lactose digestion effectively and allow for continued consumption of milk- based products. Maintaining a healthy gastrointestinal flora helps support brush border function and digestive capacity as well.
Digestion of Plant-Based Compounds
Digestxyme contains several principle digestive enzymes as well as a complement of enzymes designed to break down plant compounds and fibers that humans would otherwise be unable to digest. Raffinose and melibiose, carbohydrates commonly found in legumes, can be broken down by the intestinal enzyme alpha- galactosidase. In the absence of this enzyme, these carbohydrates pass into the large intestine, where microbes can ferment them and produce volatile gases. Exogenous administration of alpha-galactosidase, present in Digestxyme, supports the digestion of these plant-based compounds and has been used safely and effectively. Beta-glucanase, hemicellulase, pectinase, xylanase, and dipeptidyl peptidase (DPPIV) are also present and improve the digestibility of plant-based foods by breaking down plant cell walls, fibers, and proteins. Phytase is present to facilitate the breakdown of indigestible phytates from grains and seeds, and release phosphorus, calcium, inositol, and other nutrients for absorption. Bromelain and papain offer additional support for protein digestion. The enzyme invertase catalyzes sugar to glucose and fructose. Digestxyme incorporates amylase, lipase, proteases, hemicellulase, bromelain, papain, lactase, DPPIV, and other key digestive enzymes to provide a comprehensive formulation that functions in a wide pH range to support and facilitate healthy digestion. It has been formulated to allow flexible dosing that can be adjusted for individual needs.
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