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Immune support’s active ingredient is beta 1,3/1,6 glucan, a unique complex carbohydrate purified from
Saccharomyces cerevisiae (baker’s yeast). It is natural, not genetically modified (non-GMO), hypoallergenic,
patented, and generally recognized as safe (GRAS). Taken orally, Immune support, without over-stimulating,
primes and mobilizes cells in the body’s first line of defense to enhance protection against harmful effects
of lifestyle and physical stressors.
A systematic review assessing the effects of ashwagandha for anxiety and stress response included five randomized controlled human trials. An analysis of results indicated that ashwagandha intervention resulted in greater score improvements than placebo in outcomes shown on anxiety or stress scales, with no observed adverse events.
SHODEN® INDUSTRY-LEADING CONCENTRATION SUPPORTS A MORE RESTFUL NIGHT SLEEP
Shoden® Ashwagandha Extract Shoden is an extract derived from the leaves and roots of the ashwagandha plant. This multi-patented ashwagandha extract is distinguished by its industry-leading concentration of 35% withanolide glycosides. Shoden has been clinically studied for its adaptogenic role in the stress response and for support of a more restful night sleep. Additionally, studies designed specifically to assess the safety of Shoden resulted in no adverse or toxic effects. Company Name’s Ashwagandha Complete contains 240 mg of Shoden per the two-capsule daily dose.
A randomized, double-blind, placebo-controlled trial in adults (N = 60) was designed to assess the stress-balancing effects and the potential mechanism of action of Shoden. Test subjects given 240 mg of Shoden daily for 60 days demonstrated reduced levels of the stress hormone cortisol and the steroidal hormone DHEA-S. There was also an increase of testosterone in male participants. Although other potential mechanisms of action were not investigated, the results of this study suggested ashwagandha has an attenuating effect on the hypothalamic-pituitary-adrenal axis activity in stressed individuals.
Results from a randomized, controlled trial in adult males (N = 57) with moderate fatigue who were given Shoden daily for 16 weeks indicated significant improvements in salivary levels of the steroid hormones DHEA-S and testosterone, which typically decline with age. Additionally, although insignificant, self-reported improvements in fatigue, vigor, and sexual and psychological well-being were documented via questionnaire. No significant difference was recorded for salivary cortisol levels; however, it should be noted that in previous findings serum rather than salivary cortisol was assessed.
To ascertain the effect of Shoden on restorative sleep, healthy subjects (N = 150) were given 120 mg of Shoden daily for 6 weeks in a double-blind, placebo-controlled study. The overall quality of sleep was evaluated using a weekly questionnaire and an assessment of parameters such as sleep latency, sleep efficiency, and total sleep time as measured by a wearable sleep actigraphy diagnostic monitoring device. A significant improvement of sleep measures that define non-restorative sleep were noted in the treatment group when compared to placebo, demonstrating the positive effect of Shoden on encouraging restful sleep.
For ongoing immune support: Take one capsule daily, first thing in the morning or last thing at night (before or well after a meal), with a full 8 oz glass of water.
For fast-acting immune support: Take up to two capsules per day, as above, or as directed by your healthcare professional.
FORMULATED TO EXCLUDE
Wheat, gluten, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified
organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Distributed By InnerLight Remedies
1410 Northern Blvd #1013
Manhasset, NY 11030
WHEN WILL MY ORDER SHIP
Orders generally ship within 48 hours of purchase. During times of higher traffic, such as the release of a new product, this time may be extended.
Free shipping for US and For International Order Shipping fees vary by product and quantity. Please review your cart before submitting your order for accu-
rate shipping costs.
SHIPPING TIME FRAME
Domestic orders are normally delivered within 5-7 business days from the ship date. International orders are normally delivered within 2-4 weeks from the
ship date. Please keep in mind that this is from ship date, not order date. This also does not include customs processing time for
Beta-glucan has been recognized for its support of immune system activity for centuries; and yeast-derived beta-glucan has become the subject of over 800 scientific studies to date. Immune support contains concentrated beta-glucan from the yeast Saccharomyces cerevisiae, a source known to support immune function. Beta-glucan is produced by fungi, grains, seaweed, and yeast, but not by mammalian cells. While each source of beta-glucan has its own unique structure of glucose linkages, purified yeast-derived beta-glucan from S cerevisiae is considered the most effective source. Purity of the product is vital, since protein contaminants can cause untoward immune reactions. InnerLight Remedies’s Immune support 500 is refined to remove most impurities, including proteins and fats that can interfere with uptake and effectiveness. Mannan, a potential trigger of allergic reactions or bowel exacerbation, has been removed. Immune support 250 provides 250 mg beta-glucan per capsule, while Immune support 500 provides 500 mg beta-glucan per capsule. Ongoing research has unveiled a detailed mechanism of action, including activation of macrophages, neutrophils, and T-cell–mediated immunity. Orally administered yeast beta-glucan is processed by macrophages—the first line of defense in cellular immunity with subsequent increases in phagocytosis, selective cytokine release, and oxidative degranulation. Macrophages degrade beta-glucan into small fragments that are then bound to neutrophils (granulocytes), the most abundant immune cells in the body. Neutrophils then become primed and are better able to provide support against microbial challenges. Through a process called chemotaxis, these primed neutrophils migrate to target sites with enhanced immune actions. Prophylactic administration of beta-glucan was found to positively affect levels of the antioxidant enzymes catalase and superoxide dismutase, moderate tissue-damaging cytokines, and assist in ameliorating microbial imbalance. Research demonstrates a sustained release of soluble fragments over a multi-day period, providing a unique mechanism of action for the beta-glucan form found in Immune support 500. Studies also indicate that the entrance of these soluble fragments into the bone marrow may affect white-blood–cell recovery, further enhancing its health effects. Individuals at increased risk for immune challenges, those in need of immune support, or those undergoing surgery have been found to benefit from Immune support 500 week, randomized, phase II, double-blind, placebo controlled, parallel-group trial of beta-glucan from S cerevisiae was conducted. Long-term use of beta-glucan was well tolerated and resulted in a reduction in acute immune challenge discomforts.
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