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• Supports Healthy Brain Magnesium Levels
• Supports Healthy Synapse Number and Function
• Supports Cognitive Health
• Supports Stress Management, Sleep Quality, and a Healthy Mood
• Helps Ensure an Optimal Magnesium Intake for Overall Health
$74.00 USD $99.00 USD You save: 25% ( $25.00 USD )
A systematic review assessing the effects of ashwagandha for anxiety and stress response included five randomized controlled human trials. An analysis of results indicated that ashwagandha intervention resulted in greater score improvements than placebo in outcomes shown on anxiety or stress scales, with no observed adverse events.
SHODEN® INDUSTRY-LEADING CONCENTRATION SUPPORTS A MORE RESTFUL NIGHT SLEEP
Shoden® Ashwagandha Extract Shoden is an extract derived from the leaves and roots of the ashwagandha plant. This multi-patented ashwagandha extract is distinguished by its industry-leading concentration of 35% withanolide glycosides. Shoden has been clinically studied for its adaptogenic role in the stress response and for support of a more restful night sleep. Additionally, studies designed specifically to assess the safety of Shoden resulted in no adverse or toxic effects. Company Name’s Ashwagandha Complete contains 240 mg of Shoden per the two-capsule daily dose.
A randomized, double-blind, placebo-controlled trial in adults (N = 60) was designed to assess the stress-balancing effects and the potential mechanism of action of Shoden. Test subjects given 240 mg of Shoden daily for 60 days demonstrated reduced levels of the stress hormone cortisol and the steroidal hormone DHEA-S. There was also an increase of testosterone in male participants. Although other potential mechanisms of action were not investigated, the results of this study suggested ashwagandha has an attenuating effect on the hypothalamic-pituitary-adrenal axis activity in stressed individuals.
Results from a randomized, controlled trial in adult males (N = 57) with moderate fatigue who were given Shoden daily for 16 weeks indicated significant improvements in salivary levels of the steroid hormones DHEA-S and testosterone, which typically decline with age. Additionally, although insignificant, self-reported improvements in fatigue, vigor, and sexual and psychological well-being were documented via questionnaire. No significant difference was recorded for salivary cortisol levels; however, it should be noted that in previous findings serum rather than salivary cortisol was assessed.
To ascertain the effect of Shoden on restorative sleep, healthy subjects (N = 150) were given 120 mg of Shoden daily for 6 weeks in a double-blind, placebo-controlled study. The overall quality of sleep was evaluated using a weekly questionnaire and an assessment of parameters such as sleep latency, sleep efficiency, and total sleep time as measured by a wearable sleep actigraphy diagnostic monitoring device. A significant improvement of sleep measures that define non-restorative sleep were noted in the treatment group when compared to placebo, demonstrating the positive effect of Shoden on encouraging restful sleep.
Dissolve one level scoop in 4 oz water and consume once or twice daily, or as directed by your healthcare professional.
FORMULATED TO EXCLUDE
Wheat, gluten, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified
organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Distributed By InnerLight Remedies
1410 Northern Blvd #1013
Manhasset, NY 11030
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NeuroMag – Optimizes Magnesium Delivery to Body and Brain
Dietary intakes of magnesium are consistently below minimum recommended levels, and an insufficiency of magnesium is implicated in a wide range of health concerns, including those that affect the brain. Because many forms of magnesium have low bioavailability, InnerLight Remedies carefully selected magnesium compounds backed by research and studies to formulate NeuroMag. Built upon the long-term clinical success of Magnesium Chelate, NeuroMag features a unique combination of Magnesium Chelate’s highly absorbable, organic Albion minerals di-magnesium malate and TRAACS magnesium lysinate glycinate chelate and MagteinTM. Magtein is a groundbreaking organic magnesium compound that was developed by MIT (Massachusetts Institute of Technology) researchers to support “brain power.”
Magtein – Patented Magnesium L-Threonate
Magtein is the result of 10 years of research at MIT. This novel form of magnesium is changing the way we support brain health. Unlike other brain products on the market that work via brain stimulation (often overstimulation), Magtein works via a completely different mechanism. When brain magnesium levels are not optimal, synapse function deteriorates. By delivering magnesium into synapses, Magtein helps brain cells stay healthy, without being overactivated; consequently, brain cells respond to signals with clarity and robustness.
Magtein Raises Brain Magnesium Levels
Studies show that Magtein crosses the blood-brain barrier and raises the brain’s magnesium levels, which result in increased magnesium deposits in neural synapses, increased neural synaptic density, and improved brain function. One animal study showed that when the bioavailability of several magnesium compounds was compared to controls, only Magtein significantly enhanced magnesium bioavailability and produced a significant increase (7% to 15%) in rat cerebrospinal fluid. These small but significant increases in brain magnesium levels produced profound effects on neurological function.
Magtein Supports Healthy Synaptic Number and Function
Maintaining extracellular magnesium in the brain helps preserve synaptic density and keeps the synapses working properly. By increasing magnesium concentration in the extracellular fluid, researchers observed permanent enhancement of synaptic plasticity in networks of cultured hippocampal neurons. Delving deeper into the mechanisms involved, later animal research showed that magnesium increased receptor signaling; specifically, the signaling of the NR2B-containing N-methyl-D-aspartate (NMDA) receptor. NMDA receptors are rich in the hippocampus and play a pivotal role in memory processes. Data from these studies suggest that increasing brain magnesium with Magtein “enhances both short-term synaptic facilitation and long-term potentiation and thereby supports synaptic plasticity and learning and memory functions in rats.
Magtein Supports Cognitive Health
The cognitive effects of Magtein were studied by Liu et al in a randomized, double-blind, placebo-controlled trial (n = 51). At a dose of 1.5g/d to 2 g/d (25 mg/kg/d) for 12 weeks, patients 50-70 years of age taking Magtein demonstrated reduced cognitive declines compared to age-matched controls. Furthermore, the researchers calculated a particularly compelling impact of Magtein using normative TMT data from age-matched subjects: After six weeks of treatment, the average brain age of the Magtein group decreased from 69.6 ± 4.2 years to 60.6 ± 5.6 years, an improvement of 9.0 ± 3.5 years, and persisted after 12 weeks of treatment with 9.4 ± 3.5 years of improvement. These clinical benefits have been supported by the data of several animal studies. Several pre-clinical animal studies that used assessments such as the NORT (novel object recognition test), T-maze, Morris water maze, conditioned fear memory, and conditioned taste aversion have also validated Magtein’s effectiveness. The Trail Making Test - Part B (TMT-B) assesses executive function as well as impulsivity, visual search, visual attention, and motor speed. In these studies, researchers demonstrated that when brain magnesium levels were increased, significant benefits were detected in multiple aspects of learning and memory in young and aged rodents. For instance, NORT tests performed by Slutsky et al revealed that short-term memory improved approximately 135% and long-term memory improved approximately 85% in aged rats treated with Magtein compared to control (untreated) rats. One study examined the effects of Magtein in test mice (genetically altered mice that model age-related cognitive changes). Li et al found that the test mice not given Magtein exhibited “unequivocal learning deficits,” while the test mice given Magtein performed similarly to normal mice. In short, Magtein helped preserve normal brain function. When magnesium levels in the brain tissue were quantified, the relationship became even clearer: According to researchers, brain magnesium levels positively correlated with cognitive function; that is, the lower a mouse’s brain magnesium level, the poorer its memory function in the NORT task. Furthermore, histological analysis of brain tissue showed that Magtein administration preserved synapse density and NMDA receptor signaling and also had positive effects on the expression of certain proteins associated with changes in memory.
Magnesium in Stress Management, Sleep Quality, and Mood
Magnesium is known to benefit the body in ways that counter stress, promote restful sleep, and support a healthy mood. In rats, magnesium administration attenuated neurologic changes brought on by chronic mild stress. Additionally, by increasing fear memory extinction, Magtein showed promise as a modulator of worry. In human studies, magnesium supplementation partially reversed sleep changes associated with aging and improved objective and subjective measures of sleep. Improving sleep quality and countering the effects of chronic stress positively impact mood another area that is beneficially influenced by optimal magnesium status.
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